198 BCE

The Battle of Panium is fought between Seleucid forces led by Antiochus III and Ptolemaic forces led by Scopas of Aetolia. The Seleucids win the battle which allows Antiochus III to obtain entire possession of Palestine and Coele-Syria from King Ptolemy V of Egypt. Though the Romans send ambassadors to Ptolemy V, they are unable to lend him any serious assistance against Antiochus III. After his election to the consulship, Titus Quinctius Flamininus is chosen to replace Publius Sulpicius Galba Maximus as the leading Roman general in Macedonia. He then crosses into Macedonia with his army. Flamininus realizes that future peace depends on breaking the power of king Philip V of Macedon, not merely humbling him. He secures the backing of the Achaean League and then opens peace negotiations with Philip at Nicaea in Locris. Though peace proposals are submitted to the Roman Senate, the talks break down, and fighting resumes. Titus Quinctius Flamininus' forces manage to push Philip V out of most of Greece, except for a few fortresses. He then defeats Philip V in the Battle of the Aous, near modern Tepelenë in Albania.

In the 190s BC, the 2nd century BC.