Upper Mesopotamia

northern portion of region between Tigris and Euphrates rivers, now part of Iraq, Syria and Turkey

12 dated entries naming Upper Mesopotamia, drawn from 12 separate years between 602 CE and 1200 CE. Nothing here is written by us: each line is the sentence a Wikipedia year article used, and the link beside it opens the exact revision.

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7th century

602Byzantine–Persian War: King Khosrau II launches an offensive against Constantinople, to avenge Maurice's death, his "friend and father", and tries to reconquer Byzantine territory. Narses, governor of Upper Mesopotamia, rebels against Phocas at the city of Edessa and requests aid from the Persians. Khosrau sends an expeditionary force to Armenia and crosses the Euphrates.source

8th century

746August or September – Battle of Kafartuta: Caliph Marwan II defeats and kills Al-Dahhak ibn Qays al-Shaybani, leader of the Kharijites, in Upper Mesopotamia. The rebels withdraw across the River Tigris, escaping destruction.source

9th century

866The Kharijite revolt against the Abbasid Caliphate begins in Al-Jazira (Upper Mesopotamia), which will last for 30 years.source
893Spring – Caliph Al-Mu'tadid recognizes Khumarawayh as autonomous emir over Egypt and Syria, in exchange for an annual tribute of 300,000 dinars. The Jazira provinces of Diyar Rabi'a and Diyar Mudar are returned to the Abbasid Caliphate. Muslim forces recover direct control of Mosul (modern Iraq) from the Shayban.source
896Kharijite Rebellion: The Kharijite uprising against the Abbasid Caliphate in Jazira is ended. Caliph Al-Mu'tadid reunifies the entire province under central government, and installs his son and heir, Al-Muktafi, as governor.source
899Muhammad ibn Ahmad al-Shaybani, Muslim ruler of Diyar Bakr, surrenders at the besieged capital of Amid (modern Turkey) to Caliph Al-Mu'tadid in exchange for clemency. Al-Muktafi, the son of Al-Mu'tadid, is installed as governor of the Jazira (Upper Mesopotamia), ending the semi-independent Shaybanid Dynasty, which has ruled in Diyar Bakr since the 870s.source
900Arab–Byzantine wars: Emperor Leo VI ("the Wise") begins an offensive against the Abbasid army in Cilicia, Upper Mesopotamia and Armenia. He also continues the war against the Muslims in Sicily and southern Italy.source

10th century

944Arab–Byzantine War: Byzantine forces are defeated by Sayf al-Dawla. He captures the city of Aleppo, and extends his control over the Al-Jazira–Upper Mesopotamia region. Al-Dawla's rule is recognized by the Ikhshidids. With the recovery of Edessa, the Greeks also obtain the fabled Image of Edessa.source
972Spring – Emperor John I Tzimiskes divides the Bulgarian territories, recently held by the Kievan Rus', into six new themes. He turns his attention to the East against the Abbasid Caliphate and its vassals, beginning with an invasion of Upper Mesopotamia. John transfers Byzantine troops to Macedonia, and the region of Philippopolis in Thrace, to dilute the Slavs.source
973Spring – The Byzantine army, led by General Melias (Domestic of the Schools in the East), continues the operations in Upper Mesopotamia.source

12th century

1182September – Saladin invades the Jazira Region, ending the truce between him and the Zangids. After a feint attack on Aleppo, he crosses the Euphrates. The towns of the Jazira fall before him; the cities of Edessa, Saruj and Nisibin are captured in October. Saladin presses on to Mosul, and begins the siege of the city on November 10.source
1200February 17 – Al-Adil I, Ayyubid ruler of Damascus, Jerusalem, and parts of the Jazira takes control of Egypt, and is recognized as sultan of the Ayyubid Empire. During his reign, he promotes trade and good relations with the Crusader States. His son Al-Kamil becomes the effective ruler (viceroy) of Egypt.source